Imatinib Powder
- Product Name:4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
- CAS No.：106261-64-7
- MF: C13H19Cl3N2O
- Dosaggio: 99%
- Aspetto: polvere bianca
- Molecular Weight: 325.66
- I nostri imballaggi: 25 kg/barile, 10 kg/25 kg/cartone, 1 kg/5 kg/10 kg/sacco o su richiesta
Dettagli del prodotto
Imatinib powder is used to treat all stages of chronic myeloid leukemia (CML), and it is also used to treat CD117-positive gastrointestinal stromal cell tumor (GIST). It is a small molecule protein tyrosine kinase inhibitor that can effectively inhibit the activity of BCR-ABL tyrosine kinase (TK) and the following TK receptors: Kit, stem cells encoded by the c-Kit proto-oncogene Factor (SCF) receptors, discoid domain receptors (DDR1 and DDR2), colony-stimulating factor receptors (CSF-1R), and platelet-derived growth factor receptors alpha and beta (PDGFR-alpha and PDGFR-beta).
Imatinib also inhibits the cellular behavior mediated by activation of these receptor kinases. In addition, imatinib can inhibit platelet-derived growth factor (PDGF) receptor, stem cell factor (SCF), tyrosine kinase of c-Kit receptor, thereby inhibiting cell behavior mediated by PDGF and stem cell factor. Imatinib-Intermediates,4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride, is a white powder, an indispensable key body for the synthesis of imatinib.
Benefici per la salute
- For the treatment of the chronic phase, accelerated phase or blast phase of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+CML).
- For the treatment of adult patients with unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST).
- Combined chemotherapy for the treatment of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).
- For the treatment of adult patients with relapsed and refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).
* Questa affermazione ha solo scopo informativo. Non è stata valutata dalla Food and Drug Administration. Questo prodotto non è destinato a diagnosticare, trattare, curare o prevenire alcuna malattia.
