5-Fluoro-2-oxindole

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5-Fluoro-2-oxindole (CAS: 56341-41-4) is a high-quality chemical intermediate with the molecular formula C8H6FNO and a molecular weight of 151.14. It appears as a white to pale brown powder or crystalline powder, with a melting point of 143-147°C and a predicted boiling point of 307.2±42.0°C. This compound is stable under recommended storage conditions and should be kept cold to maintain its integrity. 5-Fluoro-2-oxindole is a versatile compound widely used in pharmaceutical intermediates, it serves as a valuable intermediate in the synthesis of various pharmaceuticals. It has been studied for its biological activities, including anti-inflammatory, antioxidant, anxiolytic, antidepressant, and antinociceptive effects. We offer this chemical in multiple package sizes from research quantities to industrial bulk. Each batch comes with detailed analysis certificates and safety documentation.

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This compound is utilized in the production of sunitinib, a medication approved for the treatment of certain cancers, including metastatic renal cell carcinoma and gastrointestinal stromal tumors. Derivatives of 5-Fluoro-2-oxindole have been synthesized and evaluated for their potential as α-glucosidase inhibitors. Research indicates that it can inhibit neuropathic pain and modulate the expression of specific proteins in the spinal cord and paw. These studies aim to develop novel compounds that can prevent the digestion of carbohydrates, thereby reducing blood glucose levels—a strategy relevant to managing conditions like diabetes.