Nilotinib Powder

  • Product Name:4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
  • CAS No.:917392-54-2
  • MF: C18H16N4O2
  • 검정법:99%
  • Appearance: Pale-yellow solid
  • Molecular Weight: 320.35
  • 포장: 25kg/배럴, 10kg/25kg/카톤, 1kg/5kg/10kg/가방 또는 귀하의 요청

제품 세부 정보

Nilotinib powder is a second-generation, next-generation targeted drug developed and sold by Novartis in Switzerland for the treatment of chronic myeloid leukemia. Raw powder antiacncer nilotinib powder, methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate is a key intermediate of the chemotherapeutic drug nilotinib. The drug is safe and effective in the treatment of chronic myeloid leukemia/chronic myeloid leukemia patients taking imatinib for drug resistance. It is a tyrosine kinase inhibitor, and its content mainly inhibits BCR-ABL, KIT, LCK, EPHA3, EPHA8, DDR1, DDR2, PDGFRB, MAPK11, ZAK kinases, etc. Dashina (nilotinib) is a new type of targeted tumor therapy drug, which has a significant effect on chronic myeloid leukemia (CML) patients who are resistant or intolerant to Gleevec (imatinib).

건강상의 이점

Nilotinib is a first-line oral targeted therapy for the treatment of chronic myeloid leukemia/chronic myeloid leukemia (CML).

  • Treatment of newly diagnosed Philadelphia chromosome positive (Ph+) adult chronic myeloid leukemia in the chronic phase.
  • Treatment of Philadelphia chromosome-positive chronic myeloid leukemia in blast phase and accelerated phase.
  • Treatment of chronic myeloid leukemia in the chronic phase that has been treated with interferon Chemicalbook.
  • Children with chronic myeloid leukemia who have relapsed after myelosuppression or who are ineffective in interferon therapy.
  • Treatment of KIT(CD117)-positive inoperable or metastatic malignant gastrointestinal stromal tumors.

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