Chenodeoxycholic Acid 474-25-9

Product Details

Chenodeoxychoh Acid 474-25-9 (CDCA) is the epimer of ursodeoxycholic acid with white or light yellow needle crystals, also known as deoxychenodecholic acid, its chemical name is: 3a,7a- Dihydroxy-5b-cholanoic acid is an organic compound with the chemical formula C24H40O4. It is almost insoluble in water, easily soluble in ethanol, glacial acetic acid, and slightly soluble in chloroform. It is an endogenous and hydrophobic primary bile acid. A bile acid synthesized in the liver from cholesterol.

The pharmacological research on chenodeoxycholic acid mainly focuses on the effect of dissolving cholesterol gallstones, and the research and mechanism of action at the molecular level. There are also reports. The conjugated taurine (T chenodeoxycholic acid) also has certain pharmacological effects, but it is mainly used as a valuable chemical reagent.

It is clinically used for the treatment of cholelithiasis, and it has a good dissolving effect on cholesterol and gallstones. Mainly used for the treatment of liver and gallbladder diseases, antitussive, asthma and so on. It can inhibit the activity of HMG-CoA reductase and stimulate the activity of the rate-limiting enzyme of bile acid synthesis, thereby expanding bile acid to facilitate the dissolution of cholesterol in micelle state.

It can also inhibit the excretion of cholesterol by liver cells, reducing cholesterol synthesis by a negative-reverse mechanism. It can also reduce the reabsorption of cholesterol in the small intestine. Studies have confirmed that can affect the synthesis of cholestasis, reduce the production of cholestasis in liver cells, make the ratio of bile to bile acids moderate, and has a strong choleretic effect.

What we offer are:

• Chenodeoxycholic acid 98%
• Chenodeoxycholic acid powder

Health Benefits

CDCA is generally used for patients with gallbladder cholesterol stones that are less than 2 cm in diameter and have good gallbladder function. It can inhibit intestinal absorption of water, often with diarrhea symptoms.

It is a clinically common choleretic drug for the treatment of gallstones. It is a prescription drug that should be taken under the guidance of a physician. it is a colorless needle-like crystal, has no taste, and is not easily dissolved in water. The role is currently the most important drug for the treatment of gallstones in the world, and it is the largest amount of all gallstone drugs. It is also an important raw material for the synthesis of ursodeoxycholic acid and other steroid compounds, and is widely used in clinical practice. It can dissolve cholesterol stones, and it is very effective for the treatment of gallbladder cholesterol stones with a diameter of less than 2cm and good gallbladder function.