Erlotinib Powder

Product Details

“3-Aminophenylacetylene cas 54060-30-9 99% pure anticancer erlotinib powder”. M-aminophenylacetylene is a key intermediate of the new antitumor drug erlotinib hydrochloride, and it is a colorless or pale yellow liquid. Erlotinib powder is widely used in clinical treatment of advanced lung cancer and pancreatic cancer.

The small molecule compound Erlotinib, also known as Erlotinib, Taseva, Tarceva, OSI-774, Tarceva, is a receptor tyrosine kinase inhibitor (EGFR antagonist), which belongs to molecular targeted therapy Drugs, by competing with adenosine triphosphate to bind to the catalytic site of the intracellular region of receptor tyrosine kinases in cells, inhibit phosphorylation, thereby blocking downward proliferation signaling and inhibiting tumor cell ligand-dependent HER-1 /EGFR activity, it is believed to inhibit tumor cell proliferation. Clinically, it is mainly used for the first-line treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) that is ineffective in other treatments and in combination with gemcitabine for locally advanced unresectable or metastatic pancreatic cancer.

Health Benefits

3-Aminophenylacetylene is an important intermediate for the synthesis of new quinazoline anticancer drugs and nicotinic acid herbicides; it is also an active end-capping group raw material for thermosetting polyimide resin modification, and the material has excellent heat resistance. and mechanical properties, no volatile substances are generated during curing and molding, the product has small porosity and good wear resistance, and is a high-end resin used in aerospace and military fields. It can effectively improve the clarity of various negative films; in immunoassays, m-aminophenylacetylene-derived indole compounds are important fluorescent markers; in addition, this product can also be used as a high-temperature resistant adhesive or high-temperature resistant varnish alone.